CVD risk is reversed after 5-10 years of no smoking
Blood pressure should be prior to drug treatment
120 mmHg is used for baseline risk
Only applies if SBP is greater than 120 mmHg
Cholesterol should be prior to drug treatment
3 mmol/L is used for baseline risk.
Click to change to mg/dL.
116 mg/dL is used for baseline risk.
Click to change to mmol/L.
HDL should be prior to drug treatment
1.3 mmol/L is used for baseline risk.
50 mg/dL is used for baseline risk.
Angina or heart attack in a 1st degree relative < 60 yrs
BMI of 25 kg/m2 for baseline risk
The amount of additional risk conferred from a family member to a patient depends on: (1) how close a relative, (2) age of a relative, (3) number of affected family members.
If mother (< 65 yrs) increase risk 60%
If father (< 55 yrs) increase risk 75%
Benefit often has nothing to do with the effect on the surrogate marker. At present, you can only select one intervention at a time.
|Total with an event|
|Number who benefit from treatment|
|NNT||Number needed to treat|
|Baseline events using baseline factors alone|
|Additional events “caused” by risk factors|
As with all risk calculators, calculated risk numbers are +/- 5% at best. More information.
See the QRISK®2 disclaimer for more information.